Fertility drugs

Useful information on the three main types of fertility drugs used to promote ovulation and thus increase the chances of conception, including hMG and Clomiphene.
Fertility drugs work by stimulating hormones in a woman's brain to get an egg ready and release it from her ovaries each month, thus promoting ovulation. Many fertility drugs have been used safely and successfully for more than 30 years. Unlike many other infertility solutions, such as in vitro fertilisation, fertility drugs will not increase the chance of multiple births beyond 5 to 15 percent. The most common fertility drugs include Clomiphene, Human Menopausal Gonadotrophin, and Bromocriptine.

Clomiphene, taken in pill form daily, stimulates the pituitary gland to produce follicle-stimulating hormones, which are the hormones that trigger ovulation. It prompts the ovaries to prepare a number of eggs for ovulation. Once the drug cycle is finished, the hypothalamus gland releases a lutenizing hormone, which instructs the ovaries to release a mature egg from its follicle to the Fallopian Tubes. Women who ovulate irregularly or not at all commonly use Clomiphene. Clomiphene can cause a wide range of side effects, including mood swings, dry cervical mucus, mild ovarian enlargement, stomach pain, breast and ovarian cancer. About 70 to 90 percent of women who take Clomiphene will ovulate, and of those who ovulate, 20 to 60 percent will get pregnant.

Human Menopausal Gonadotropin (hMG) consists of purified follicle stimulating hormone (FSH). When injected into the body, FSH causes a woman to develop egg follicles. After seven to twelve days of shots, the woman receives an injection of human chorionic gonadotropin that stimulates the ovaries to release the egg or eggs it has just developed. HMG is most often given to women with low oestrogen levels who have not responded to Clomiphene. Possible side effects from hMG include abdominal tenderness and weight gain. In rare cases, less than 5 percent of the time, women develop hyper stimulated ovaries, a potentially fatal condition signalled by sudden onset of severe pelvic pain, nausea, vomiting, or weight gain. Due to an excessive number of eggs, the ovaries rapidly swell to several times their size and may leak fluid into the abdominal cavity. Even with careful monitoring, multiple pregnancies and ovarian hyper stimulation can occur. The rate of multiple births is close to 20 percent. About 70 to 90 percent of women who take hGM will ovulate, and of those who ovulate, 20 to 60 percent will get pregnant.

Bromocriptine, which can be taken orally or as a vaginal pill, reduces the pituitary gland's production of the hormone prolactin. Excess prolactin reduces oestrogen levels and inhibits ovulation. Women who take Bromocriptine usually suffer from hyperprolactinemic amenorrhea, which is a condition where ovulation problems are caused by a pituitary adenoma (a benign tumour). Side effects from Bromocriptine include nausea, dizziness, low blood pressure, and headaches. Patients who take the drug vaginally often report fewer side effects. 90 percent of the women who take Bromocriptine will ovulate as long as they continue taking the drug. Of the women who ovulate, 65 to 85 percent will get pregnant.

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We have been trying to fall preg for a year now. we decided to use Pregnacare to boost my fertility..this is my second month using them and nothing. i have started my periods yesterday the 19th May. im now getting worried, Pls advise
by Oletilwe 20th Jun 2013, 3:48pm
Pls i have use pills for long, since i stop using it my monthly period ceased, pls i want to know the drugs i can take so that i can get pregnant.
by Honey24 20th Jun 2013, 3:44pm
i have used clomid twice! First time it took 4 cycles to work and then i was pregnant with my son who is now 21 months. I then used clomid again and it worked first month i was shocked! I'm now 15 weeks pregnant. Before using clomid my partner and i tried 4 years naturally with no luck so please dont give up hope and dont wait so long to get help! I wish you all success x
by karlieann 25th Feb 2011, 5:06pm
What are the drugs names
by nakia 27th Oct 2010, 9:25am
where do you get these drugs from please?
by babystar 6th Oct 2010, 9:32am
Hi, we have been trying to concieve for 4yrs now, this year i had a miscarriage (natural conception), i was put on clomid but after 6mths and it not working the consultant said it was the end of the line and i should think about ivf, as this isnt an option unless we save for afew years i just wondered if anyone knew about the drugs HCG or HMG and how i can get my doctor to give it me? Short of begging ive tried everything for them to give me more clomid with no avail now i feel like they have all given up but me and i dont know how many knock backs i can take...somebody help!!
Also since my miscarriage in march i havent ovulated according to the home kits but ive still had regular periods, are the home kits accurate does anyone know? I did the tests daily until my next period too
Any help will be much appreciated!!
by dawnj 27th Aug 2010, 5:09pm
im taking floric acid and i was wondering if its actually going to do anything? me and my partner are trying for a baby and im trying whatever i can.
by Rizz 12th Aug 2010, 10:28am
hi every one, sooooo stressed, me and my husband have been tryin for nearly 2 years, sum times i hav a peroid and others i dont, soooo confused :( can any one help me with a bit of advice? x
by misirish 12th Aug 2010, 9:20am
Hi I was on the depo injection and came off it 2.5 years ago. I have still not regained my periods and stopped ovulating, even though i had no problems before i started the depo. My husband and i have tried for a long time to get pregnant using clomifene but had no luck. I responded to my daily injections within a week and a half and I had my first IUI done on 12th October and am going in for a pregnancy blood test on Monday (26th October). Very nervous as i dont want to get too excited incase it's a negative result. I have very tender boobs, cramping and sometimes feel slightly dizzy but not sure if these symptoms are just caused by the two HCG injections I have taken after IUI. How early can you start getting symptoms? Anyone having the same sort of experience?
by Drekie 22nd Oct 2009, 9:19am
where do you get these drugs from does anyone know? and do they work?
by elle4dan 4th Sep 2009, 10:33am
if i want to be pragnent then then what should i do for stopping my periods/ what should i eat and what i have to not do this time/ what are the instructions about this matter? i need pragnancy/ but periods comes in month and finished everythings please tell me what is forbidden for me not to eat and tell me more about this matter please/ kindely request it sombody help me
by 9838614128 10th Aug 2009, 9:26am
GOOD LUCK EVEYONE :)
by ShareenElliisBabyx 8th Jun 2009, 9:42am
I recently started ovulation induction shots to get pregnant. I was giving myself a shot every night of Follistim, is anyone else familiar with this medication? I am now waiting 2 weeks before I can take a pregnancy test (doctors orders) thay don't want me to get a false positive. Its killing me to wait but Im hoping and praying that I am because the medication is very expensive and lucky for me I got to do it for free the frist time around as a trial study, we won't be able to try again for awhile if I am not. We will have to save up for it. I need everyones prayers
by weddingbliss 14th May 2009, 9:43am
i was taking 100mg of clomid a day for five days for three months and then my cycles stopped again. I upped the dose to 150 a day and my new consultant told me that if it didn't work after 3 cycles it wasn't for me. I am now starting the gonal f injections this month. hope this helps
by katrinamc 20th Apr 2009, 9:33am
I have been using clomiphene from Iwas 29 years old Iam now 32 years old I have changed partners I still cannot get pregnant I am depressed Ionly menstrate for three days. I have now missed my periods but I am afraid to do the pregnancy test in case Imight be disapointed again.
by nugzy 1st Apr 2009, 9:42am
HI,
Does anyone knows how long a treatment on clomiphene will take to be effective and be able to conceive. your reply will be highly appreciated.
by tayo 16th Sep 2008, 9:00am

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